In Vitro Selection of Single-Stranded DNA Molecular Recognition Elements against S. aureus Alpha Toxin and Sensitive Detection in Human Serum

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Ka L. Hong; Luisa Battistella; Alysia D. Salva; Ryan M. Williams; Letha J. Sooter;
  • Publisher: MDPI AG
  • Journal: International Journal of Molecular Sciences,volume 16,issue 2,pages2,794-2,809 (issn: 1422-0067, eissn: 1422-0067)
  • Related identifiers: doi: 10.3390/ijms16022794, pmc: PMC4346865
  • Subject: Chemistry | <i> in vitro</i> selection | QD1-999 | SELEX | molecular recognition element (MRE) | Article | QH301-705.5 | ELISA | <i>Staphylococcus aureus</i> | aptamer | in vitro selection | alpha toxin | ssDNA | Biology (General) | Staphylococcus aureus

Alpha toxin is one of the major virulence factors secreted by Staphylococcus aureus, a bacterium that is responsible for a wide variety of infections in both community and hospital settings. Due to the prevalence of S. aureus related infections and the emergence of meth... View more
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