Peripheral surgical wounding may induce cognitive impairment through interlukin-6-dependent mechanisms in aged mice
- Publisher: Medknow Publications & Media Pvt Ltd
Medical Gas Research,
(issn: 2045-9912, eissn: 2045-9912)
Original Article | cognition | fear conditioning system | peripheral surgical wounding; interlukin-6; cognition; mice; fear conditioning system; neuroinflammation | Anesthesiology | peripheral surgical wounding | neuroinflammation | mice | RD78.3-87.3 | interlukin-6
Post-operative cognitive dysfunction (POCD) is associated with morbidity, mortality and increased cost of medical care. However, the neuropathogenesis and targeted interventions of POCD remain largely to be determined. We have found that the peripheral surgical wounding...