publication . Article . 2015

Formulation approaches to pediatric oral drug delivery: benefits and limitations of current platforms

Lopez, Felipe L; Ernest, Terry B; Tuleu, Catherine; Gul, Mine Orlu;
Open Access
  • Published: 01 Jul 2015 Journal: Expert Opinion on Drug Delivery, volume 12, pages 1,727-1,740 (issn: 1742-5247, eissn: 1744-7593, Copyright policy)
  • Publisher: Informa Healthcare
Introduction: Most conventional drug delivery systems are not acceptable for pediatric patients as they differ in their developmental status and dosing requirements from other subsets of the population. Technology platforms are required to aid the development of age-appropriate medicines to maximize patient acceptability while maintaining safety, efficacy, accessibility and affordability. Areas covered: The current approaches and novel developments in the field of age-appropriate drug delivery for pediatric patients are critically discussed including patient-centric formulations, administration devices and packaging systems. Expert opinion: Despite the incentive...
free text keywords: Pharmacology, Harmonization, Population, education.field_of_study, education, Incentive, New product development, business.industry, business, Drug development, Drug delivery, Dosing, Medicine, Review, Reviews, acceptability, age-appropriate, formulation development, oral drug delivery system, pediatric drug delivery, technology platform
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