Establishment of lipofection for studying miRNA function in human adipocytes.
- Publisher: Public Library of Science (PLoS)
(issn: 1932-6203, eissn: 1932-6203)
Lipids | Research Article | Biology and life sciences | Molecular Cell Biology | RNA | Synthetic Nucleic Acids | Medicine | Nucleic Acids | Epigenetics | Lipid Mediators | Q | R | Cell Biology | Genetics | Biochemistry | Science | RNA interference | Gene Expression
miRNA dysregulation has recently been linked to human obesity and its related complications such as type 2 diabetes. In order to study miRNA function in human adipocytes, we aimed for the modulation of mature miRNA concentration in these cells. Adipocytes, however, tend...