Effects of a 5-HT3 antagonist, ondansetron, on fasting and postprandial small bowel water content assessed by magnetic resonance imaging

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Marciani, Luca; Wright, Jeff; Foley, Stephen; Hoad, Caroline L; Totman, John J; Bush, Debbie; Hartley, Caroline; Armstrong, Alexander; Manby, Paul; Blackshaw, Elaine; Perkins, Alan C; Gowland, Penny A; Spiller, Robin;

International audience; Background 5-HT3 antagonists have been shown to be effective in relieving symptoms of IBS-D. Using a recently validated MRI method we have demonstrated reduced fasting small bowel water content (SBWC) in IBS-D associated with accelerated small bo... View more
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