Ex Vivo Spleen and Kidney Absorption of Xenoreactive Natural Antibodies Decreases Severity of Hyperacute Rejection in Pig-to-dog Renal Xenotransplantation

Research, Article English OPEN
Nitta, Kohsaku;
  • Publisher: Hiroshima University Medical Press
  • Journal: Hiroshima Journal of Medical Sciences, volume 45, issue 4, pages 119-125 (issn: 0018-2052)
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  • Subject: Organ Absorption | Renal Xenotransplantation | 490 | Hyperacute Rejection

The severe hyperacute rejection in pig-to-dog renal xenotransplantation is mainly caused by xenoreactive natural antibodies (NAb). Organ absorption (ex vivo perfusion of spleen and kidney of donor species) was performed to remove xenoreactive NAb. A pig-to-dog renal tra... View more
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