Protein Kinases and Transcription Factors Activation in Response to UV-Radiation of Skin: Implications for Carcinogenesis

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Laurence A. Marchat ; Elena Aréchaga Ocampo ; Mavil López Casamichana ; Carlos Pérez-Plasencia ; César López-Camarillo ; Elizbeth Álvarez-Sánchez (2011)
  • Publisher: MDPI AG
  • Journal: International Journal of Molecular Sciences, volume 13, issue 1, pages 142-172 (issn: 1422-0067, eissn: 1422-0067)
  • Related identifiers: doi: 10.3390/ijms13010142, pmc: PMC3269678
  • Subject: NF-κB | Chemistry | skin cancer | JNK | QD1-999 | ERK1/2 | skin photoaging | QH301-705.5 | ultraviolet radiation | p38 | Review | ATM | SKR kinases | NRF2 transcription factors | MAPK | AP-1 | Biology (General)

Solar ultraviolet (UV) radiation is an important environmental factor that leads to immune suppression, inflammation, photoaging, and skin carcinogenesis. Here, we reviewed the specific signal transduction pathways and transcription factors involved in the cellular resp... View more
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