Recurrent bottlenecks in the malaria life cycle obscure signals of positive selection

Article English OPEN
Chang, Hsiao-Han; Hartl, Daniel L.;
(2014)

SUMMARY Detecting signals of selection in the genome of malaria parasites is a key to identify targets for drug and vaccine development. Malaria parasites have a unique life cycle alternating between vector and host organism with a population bottleneck at each transiti... View more