Grass Carp Laboratory of Genetics and Physiology 2 Serves As a Negative Regulator in Retinoic Acid-Inducible Gene I- and Melanoma Differentiation-Associated Gene 5-Mediated Antiviral Signaling in Resting State and Early Stage of Grass Carp Reovirus Infection

Article English OPEN
Rao, Youliang ; Wan, Quanyuan ; Yang, Chunrong ; Su, Jianguo (2017)
  • Publisher: Frontiers Media S.A.
  • Journal: Frontiers in Immunology, volume 8 (issn: 1664-3224, eissn: 1664-3224)
  • Related identifiers: doi: 10.3389/fimmu.2017.00352, pmc: PMC5366347
  • Subject: grass carp (Ctenopharyngodon idella) | grass carp reovirus | innate immunity | interferon regulatory factor 3 | Original Research | laboratory of genetics and physiology 2 | IRF7 | Immunology | RLRs
    mesheuropmc: viruses

Laboratory of genetics and physiology 2 (LGP2) is a key component of RIG-I-like receptors (RLRs). However, the lack of the caspase recruitment domains (CARDs) results in its controversial functional performance as a negative or positive regulator in antiviral responses.... View more
Share - Bookmark