publication . Article . 2019

Two-dimensional simulation of optical coherence tomography images

Thomas Brenner; Peter R. T. Munro; Benjamin Krüger; Alwin Kienle;
Open Access
  • Published: 01 Aug 2019 Journal: Scientific Reports, volume 9 (eissn: 2045-2322, Copyright policy)
  • Publisher: Springer Science and Business Media LLC
  • Country: United Kingdom
Abstract
Abstract An algorithm for the simulation of two-dimensional spectral domain optical coherence tomography images based on Maxwell’s equations is presented. A recently developed and modified time-harmonic numerical solution of Maxwell’s equations is used to obtain scattered far fields for many wave numbers contained in the calculated spectrum. The interferometer setup with its lenses is included rigorously with Fresnel integrals and the Debye-Wolf integral. The implemented model is validated with an existing FDTD algorithm by comparing simulated tomograms of single and multiple cylindrical scatterers for perpendicular and parallel polarisation of the incident ligh...
Subjects
free text keywords: Multidisciplinary, Wavenumber, Tomography, Interferometry, Optical coherence tomography, medicine.diagnostic_test, medicine, Optics, business.industry, business, Polarization (waves), Fresnel integral, Ray, Lens (optics), law.invention, law, Physics, Article, Imaging and sensing, Computational biophysics, Computational science, Computational biophysics, Computational science, Imaging and sensing, R, Science, Q
Related Organizations
68 references, page 1 of 5

1.Drexler, W. & Fujimoto, J. G. Optical coherence tomography: technology and applications (Springer, 2008).

Knu, A. Spatially confined and temporally resolved refractive index and scattering evaluation in human skin performed with optical coherence tomography. Journal of Biomedical Optics. 2000; 5: 83-92 [OpenAIRE] [PubMed] [DOI]

Knu, A. New method for evaluation of in vivo scattering and refractive index properties obtained with optical coherence tomography. Journal of biomedical optics. 2004; 9: 265-273 [OpenAIRE] [PubMed] [DOI]

Adhi, M, Duker, JS. Optical coherence tomography–current and future applications. Current opinion in ophthalmology. 2013; 24: 213 [OpenAIRE] [PubMed] [DOI]

Welzel, J. Optical coherence tomography in dermatology: a review. Skin Research and Technology: Review article. 2001; 7: 1-9 [OpenAIRE] [DOI]

Pagnoni, A. Optical coherence tomography in dermatology. Skin Research and Technology. 1999; 5: 83-87 [DOI]

Ulrich, M. Dynamic optical coherence tomography in dermatology. Dermatology. 2016; 232: 298-311 [OpenAIRE] [PubMed] [DOI]

Yonetsu, T, Bouma, BE, Kato, K, Fujimoto, JG, Jang, I-K. Optical coherence tomography. Circulation Journal. 2013; 77: 1933-1940 [OpenAIRE] [PubMed] [DOI]

Yabushita, H. Characterization of human atherosclerosis by optical coherence tomography. Circulation. 2002; 106: 1640-1645 [OpenAIRE] [PubMed] [DOI]

10.Liang, H. et al. Optical coherence tomography in archaeological and conservation science-a new emerging field. In 1st Canterbury Workshop on Optical Coherence Tomography and Adaptive Optics, vol. 7139, 713915 (International Society for Optics and Photonics, 2008).

Targowski, P. Optical coherence tomography in art diagnostics and restoration. Applied Physics A. 2008; 92: 1-9 [OpenAIRE] [DOI]

Liang, H. En-face optical coherence tomography-a novel application of non-invasive imaging to art conservation. Optics Express. 2005; 13: 6133-6144 [PubMed] [DOI]

13.https://www.grandviewresearch.com/industry-analysis/optical-coherence-tomography-oct-market/request (Last accessed, 12:10 pm, February 9, 2019).

Yadav, R. Micrometer axial resolution oct for corneal imaging. Biomedical optics express. 2011; 2: 3037-3046 [OpenAIRE] [PubMed] [DOI]

Zhang, X. Optical computing for optical coherence tomography. Scientific reports. 2016; 6: 37286 [OpenAIRE] [PubMed] [DOI]

68 references, page 1 of 5
Abstract
Abstract An algorithm for the simulation of two-dimensional spectral domain optical coherence tomography images based on Maxwell’s equations is presented. A recently developed and modified time-harmonic numerical solution of Maxwell’s equations is used to obtain scattered far fields for many wave numbers contained in the calculated spectrum. The interferometer setup with its lenses is included rigorously with Fresnel integrals and the Debye-Wolf integral. The implemented model is validated with an existing FDTD algorithm by comparing simulated tomograms of single and multiple cylindrical scatterers for perpendicular and parallel polarisation of the incident ligh...
Subjects
free text keywords: Multidisciplinary, Wavenumber, Tomography, Interferometry, Optical coherence tomography, medicine.diagnostic_test, medicine, Optics, business.industry, business, Polarization (waves), Fresnel integral, Ray, Lens (optics), law.invention, law, Physics, Article, Imaging and sensing, Computational biophysics, Computational science, Computational biophysics, Computational science, Imaging and sensing, R, Science, Q
Related Organizations
68 references, page 1 of 5

1.Drexler, W. & Fujimoto, J. G. Optical coherence tomography: technology and applications (Springer, 2008).

Knu, A. Spatially confined and temporally resolved refractive index and scattering evaluation in human skin performed with optical coherence tomography. Journal of Biomedical Optics. 2000; 5: 83-92 [OpenAIRE] [PubMed] [DOI]

Knu, A. New method for evaluation of in vivo scattering and refractive index properties obtained with optical coherence tomography. Journal of biomedical optics. 2004; 9: 265-273 [OpenAIRE] [PubMed] [DOI]

Adhi, M, Duker, JS. Optical coherence tomography–current and future applications. Current opinion in ophthalmology. 2013; 24: 213 [OpenAIRE] [PubMed] [DOI]

Welzel, J. Optical coherence tomography in dermatology: a review. Skin Research and Technology: Review article. 2001; 7: 1-9 [OpenAIRE] [DOI]

Pagnoni, A. Optical coherence tomography in dermatology. Skin Research and Technology. 1999; 5: 83-87 [DOI]

Ulrich, M. Dynamic optical coherence tomography in dermatology. Dermatology. 2016; 232: 298-311 [OpenAIRE] [PubMed] [DOI]

Yonetsu, T, Bouma, BE, Kato, K, Fujimoto, JG, Jang, I-K. Optical coherence tomography. Circulation Journal. 2013; 77: 1933-1940 [OpenAIRE] [PubMed] [DOI]

Yabushita, H. Characterization of human atherosclerosis by optical coherence tomography. Circulation. 2002; 106: 1640-1645 [OpenAIRE] [PubMed] [DOI]

10.Liang, H. et al. Optical coherence tomography in archaeological and conservation science-a new emerging field. In 1st Canterbury Workshop on Optical Coherence Tomography and Adaptive Optics, vol. 7139, 713915 (International Society for Optics and Photonics, 2008).

Targowski, P. Optical coherence tomography in art diagnostics and restoration. Applied Physics A. 2008; 92: 1-9 [OpenAIRE] [DOI]

Liang, H. En-face optical coherence tomography-a novel application of non-invasive imaging to art conservation. Optics Express. 2005; 13: 6133-6144 [PubMed] [DOI]

13.https://www.grandviewresearch.com/industry-analysis/optical-coherence-tomography-oct-market/request (Last accessed, 12:10 pm, February 9, 2019).

Yadav, R. Micrometer axial resolution oct for corneal imaging. Biomedical optics express. 2011; 2: 3037-3046 [OpenAIRE] [PubMed] [DOI]

Zhang, X. Optical computing for optical coherence tomography. Scientific reports. 2016; 6: 37286 [OpenAIRE] [PubMed] [DOI]

68 references, page 1 of 5
Powered by OpenAIRE Research Graph
Any information missing or wrong?Report an Issue