Metallic mercury uptake by catalase Part 1 In Vitro metallic mercury uptake by various kind of animals' erythrocytes and purified human erythrocyte catalase

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劒持, 堅志 (1980)
  • Publisher: 岡山医学会
  • Journal: 岡山医学会雑誌, volume 92, issue 9-10, pages 999-1,005 (issn: 0030-1558)
  • Subject: Metallic Mercury | Catalase

The uptake of metallic mercury was studied using erythrocytes with different catalase activities taken from various kind of animals. The results were: 1) The uptake of metallic mercury by erythrocytes paralleled the activity of catalase in the erythrocytes with and without hydrogen peroxide, suggesting that the erythrocyte catalase activity is related to the uptake of metallic mercury. 2) The uptake of metallic mercury occurred not only with purified human erythrocyte catalase but also with hemolysate. 3) The uptake of metallic mercury by purified human erythrocyte catalase was inhibited by inhibitors of catalase, namely 3-amino-1,2,4-triazole, potassium cyanide and azide. It was concluded that erythrocyte catalase activity has an important role in the uptake of metallic mercury.
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