Strain-specific impact of PsaR of Streptococcus pneumoniae on global gene expression and virulence.

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Hendriksen, W.T.; Bootsma, H.J.; Diepen, A. van; Estevao, S.; Kuipers, O.P.; Groot, R. de; Hermans, P.W.M.;
(2009)
  • Subject: COLONIZATION | NASOPHARYNGEAL EPITHELIAL-CELLS | REGULATOR | PNEUMOCOCCAL-SURFACE-ADHESIN | PROTECTION | RLRA PATHOGENICITY ISLET | BINDING-PROTEIN | OXIDATIVE STRESS | LUNG INFECTION | A PSAA

Previous studies have indicated that PsaR of Streptococcus pneumoniae is a manganese-dependent regulator, negatively affecting the expression of at least seven genes. Here, we extended these observations by transcriptome and proteome analysis of psaR mutants in strains ... View more
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