Evaluation of antibacterial activity of Achyranthes aspera extract against Streptococcus mutans: An in vitro study

Article English OPEN
Yadav, Roma ; Rai, Radhika ; Yadav, Abhishek ; Pahuja, Meetika ; Solanki, Savita ; Yadav, Himani (2016)
  • Publisher: Medknow Publications & Media Pvt Ltd
  • Journal: Journal of Advanced Pharmaceutical Technology & Research, volume 7, issue 4, pages 149-152 (issn: 2231-4040, eissn: 0976-2094)
  • Related identifiers: doi: 10.4103/2231-4040.191426, pmc: PMC5052942
  • Subject: antibacterial activity | Original Article | RM1-950 | Therapeutics. Pharmacology | Streptococcus mutans | Achyranthes aspera | apamarga | chlorhexidine | Pharmacy and materia medica | RS1-441

Dental caries and periodontal diseases have historically been considered the most important global oral health burdens. Many chemicals and synthetic drugs have marked the side effects. Hence, there has been a paradigm shift from the use of modern drugs to the age-old herbs. Achyranthes aspera is one such important plant with various established pharmaceutical properties. The aim of this study was to assess the antibacterial activity of the A. aspera extract against Streptococcus mutans. Aqueous extract of A. aspera was prepared. Different concentrations of the root and stem extracts of A. aspera were transferred to the agar plates, which had been streaked with the bacterium S. mutans. The plates were incubated aerobically at 37°C for 24 h, and the zones of inhibition were measured using cup plate method. A. aspera extract showed statistically significant zones of inhibition. A. aspera showed marked antibacterial activity against S. mutans.
  • References (18)
    18 references, page 1 of 2

    WHO Oral Health Report. 2003

    Prabhat, A, Navneet, CA. Evaluation of antimicrobial activity of six medicinal plants against dental pathogens. Rep Opin. 2010; 2: 37-42

    Srivastav, S, Singh, P, Mishra, G, Jha, KK, Khosa, RL. Achyranthes aspera – An important medicinal plant: A review. J Nat Prod Plant Resour. 2011; 1: 1-14

    Kumar, SV, Sankar, P, Varatharajan, R. Anti-inflammatory activity of roots of Achyranthes aspera. Pharm Biol. 2009; 47: 973-5

    Sutar, NG, Sutar, UN, Sharma, YP, Shaikh, IK, Kshirsagar, SS. Phytochemical investigation and pharmacological screening of leaves of Achyranthes aspera L. as analgesic and antipyretic. Biosci Biotechnol Res Asia. 2008; 5: 841-4

    Tullanithi, KM, Sharmila, B, Gnanendra, TS. Preliminary phytochemical analysis and antimicrobial activity of Achyranthes aspera Linn. Int Biol Technol. 2010; 1: 35-8

    Vahabi, S, Najafi, E, Alizadeh, S. In vitro antimicrobial effects of some herbal essences against oral pathogens. J Med Plants Res. 2011; 5: 4870-8

    Navneet, P, Krishna, S. Antimicrobial activity of apamarga (Achyranthes aspera Linn.). Natl Acad Sci Lett. 2005; 28: 379-81

    Phatak, AA, Patankar, RD, Galgatte, UC, Paranjape, SY, Deshpande, AS, Pande, AK. Antimicrobial activity of a poly-herbal extract against dental micro flora. Res J Pharm Biol Chem Sci. 2011; 2: 533-9

  • Metrics
    No metrics available
Share - Bookmark