Protein Fiber Linear Dichroism for Structure Determination and Kinetics in a Low-Volume, Low-Wavelength Couette Flow Cell

Article, Other literature type English OPEN
Dafforn, Timothy R.; Rajendra, Jacindra; Halsall, David J.; Serpell, Louise C.; Rodger, Alison;

High-resolution structure determination of soluble globular proteins relies heavily on x-ray crystallography techniques. Such an approach is often ineffective for investigations into the structure of fibrous proteins as these proteins generally do not crystallize. Thus ... View more
  • References (28)
    28 references, page 1 of 3

    Aulak, K. S., E. Eldering, C. E. Hack, Y. P. T. Lubbers, R. A. Harrison, A. Mast, M. Cicardi, and A. E. Davis. 1993. A hinge region mutation in C1-inhibitor (Ala(436)-]Thr) results in nonsubstrate-like behavior and in polymerization of the molecule. J. Biol. Chem. 268:18088-18094.

    Bayley, P. M., E. B. Nielsen, and A. Schellman. 1969. Rotatory properties of molecules containing two peptide groups: theory. J. Phys. Chem. 73:228-243.

    Besley, N. A., and J. D. Hirst. 1999. Ab initio study of the of the electronic spectrum of formamide with explicit solvent. J. Am. Chem. Soc. 121:9636-9644.

    Dafforn, T. R., R. Mahadeva, P. R. Elliott, P. Sivasothy, and D. A. Lomas. 1999. A kinetic mechanism for the polymerization of alpha(1)- antitrypsin. J. Biol. Chem. 274:9548-9555.

    Davis, R. L., A. E. Shrimpton, P. D. Holohan, C. Bradshaw, D. Feiglin, G. H. Collins, P. Sonderegger, J. Kinter, L. M. Becker, F. Lacbawan, D. Krasnewich, M. Muenke, D. A. Lawrence, M. S. Yerby, C. M. Shaw, D. Gooptu, P. R. Elliott, J. T. Finch, R. W. Carrell, and D. A. Lomas. 1999. Familial dementia caused by polymerization of mutant neuroserpin. Nature. 401:376-379.

    Fratzl, P., K. Misof, I. Zizak, G. Rapp, H. Amenitsch, and S. Bernstorff. 1998. Fibrillar structure and mechanical properties of collagen. J. Struct. Biol. 122:119-122.

    Geeves, M. A., and K. C. Holmes. 1999. Structural mechanism of muscle contraction. Annu. Rev. Biochem. 68:687-728.

    Holmes, K. C., D. Popp, W. Gebhard, and W. Kabsch. 1990. Atomic model of the actin filament. Nature. 347:44-49.

    Kabsch, W., and C. Sander. 1983. Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features. Biopolymers. 22:2577-2637.

    Lomas, D. A., D. L. Evans, J. T. Finch, and R. W. Carrell. 1992. The mechanism of Z alpha 1-antitrypsin accumulation in the liver. Nature. 357:605-607.

  • Bioentities (2)
    1atn Protein Data Bank
    1qlp Protein Data Bank
  • Metrics
Share - Bookmark