Metabolic induction and early responses of mouse blastocyst developmental programming following maternal low protein diet affecting life-long health.

Article English OPEN
Eckert, Judith J.; Porter, Richard; Watkins, Adam J.; Burt, Elizabeth; Brooks, Suzanne; Leese, Henry J.; Humpherson, Peter G.; Cameron, Iain T.; Fleming, Tom P.;
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 7,issue 12 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1371/journal.pone.0052791, pmc: PMC3531326
  • Subject: Endocrine System | Animal Models | Research Article | Insulin | Reproductive System | Amino Acids | Organic Acids | Mouse | Organic Chemistry | Endocrine Physiology | Reproductive Endocrinology | Embryology | Energy Metabolism | Chemistry | Biology | Developmental Biology | Reproductive Physiology | Medicine | Anatomy and Physiology | Malnutrition | Q | Nutrition | R | Model Organisms | Science | Physiological Processes
    mesheuropmc: reproductive and urinary physiology | embryonic structures

Previously, we have shown that a maternal low protein diet, fed exclusively during the preimplantation period of mouse development (Emb-LPD), is sufficient to induce by the blastocyst stage a compensatory growth phenotype in late gestation and postnatally, correlating w... View more