Phenotypic and genotypic characterization of daptomycin-resistant methicillin-resistant Staphylococcus aureus strains: relative roles of mprF and dlt operons.

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Nagendra N Mishra; Arnold S Bayer; Christopher Weidenmaier; Timo Grau; Stefanie Wanner; Stefania Stefani; Viviana Cafiso; Taschia Bertuccio; Michael R Yeaman; Cynthia C Nast; Soo-Jin Yang;
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 9,issue 9 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: pmc: PMC4166420, doi: 10.1371/journal.pone.0107426
  • Subject: Microbial Control | Q | Bacteriology | R | Research Article | Biology and Life Sciences | Antimicrobial Resistance | Science | Microbiology | Bacterial Genes | Medicine | Gram Positive Bacteria

Development of in vivo daptomycin resistance (DAP-R) among Staphylococcus aureus clinical isolates, in association with clinical treatment failures, has become a major therapeutic problem. This issue is especially relevant to methicillin-resistant S. aureus (MRSA) strai... View more
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