Extensive Alternative Splicing of the Repressor Element Silencing Transcription Factor Linked to Cancer
Miller, Gregory M.
- Publisher: Public Library of Science
(issn: 1932-6203, eissn: 1932-6203)
Computational Biology | Molecular cell biology | Research Article | Cancer Risk Factors | RNA processing | Epigenetics | Oncology | Epidemiology | Genetics | Cancer Genetics | Genetic Causes of Cancer | Physics | Gene Splicing | Biophysics | Molecular Genetics | Biology | RNA | Medicine | Nucleic acids | Basic Cancer Research | Biomarker Epidemiology | Q | R | Gene Regulation | Science | Biochemistry | Gene expression
The repressor element silencing transcription factor (REST) is a coordinate transcriptional and epigenetic regulator which functions as a tumor suppressor or an oncogene depending on cellular context, and a truncated splice variant REST4 has been linked to various types...