Essential Oil from Cryptomeria japonica Induces Apoptosis in Human Oral Epidermoid Carcinoma Cells via Mitochondrial Stress and Activation of Caspases

Other literature type, Article English OPEN
Cha, Jeong-Dan; Kim, Ji-Young;
(2012)

Cryptomeria japonica D. Don (C. japonica) has been used in traditional medicines from Asia for a variety of indications, including liver ailments, and an antitussive, and for its antiulcer activities. We examined the cell viability and apoptosis of KB cells treated with... View more
  • References (33)
    33 references, page 1 of 4

    Gradzka, I. Mechanisms and regulation of the programmed cell death. Postepy Biochem. 2006, 52, 157-165.

    White, B.C.; Sullivan, J.M. Apoptosis. Acad. Emerg. Med. 1998, 5, 1019-1029.

    3. Roos, W.P.; Kaina, B. DNA damage-induced cell death by apoptosis. Trends Mol. Med. 2006, 12, 440-450.

    4. Wang, C.; Youle, R.J. The role of mitochondria in apoptosis. Annu. Rev. Genet. 2009, 43, 95-118.

    5. Orrenius, S. Mitochondrial regulation of apoptotic cell death. Toxicol. Lett. 2004, 149, 19-23.

    6. Nalepa, G.; Zukowska-Szczechowska, E. Caspases and apoptosis: Die and let live. Wiad. Lek. 2002, 55, 100-106.

    7. Scorrano, L.; Korsmeyer, S.J. Mechanisms of cytochrome c release by proapoptotic Bcl-2 family members. Biochem. Biophys. Res. Commun. 2003, 304, 437-444.

    8. Cho, S.G.; Choi, E.J. Apoptotic signaling pathways: Caspases and stress-activated protein kinases. J. Biochem. Mol. Biol. 2002, 35, 24-27.

    9. Crowell, P.L. Prevention and therapy of cancer by dietary monoterpenes. J. Nutr. 1999, 129, 775S-778S.

    10. Allen, R.T.; Hunter, W.J., 3rd; Agrawal, D.K. Morphological and biochemical characterization and analysis of apoptosis. J. Pharmacol. Toxicol. Methods 1997, 37, 215-228.

  • Related Organizations (2)
  • Metrics
Share - Bookmark