Associations between branched chain amino acid intake and biomarkers of adiposity and cardiometabolic health independent of genetic factors: a twin study

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Jennings, Amy ; MacGregor, Alex ; Pallister, Tess ; Spector, Tim ; Cassidy, Aedin (2016)
  • Publisher: Elsevier BV
  • Journal: volume 223, pages 992-998 (issn: 0167-5273, eissn: 1874-1754)
  • Related identifiers: doi: 10.1016/j.ijcard.2016.08.307, pmc: PMC5074005
  • Subject: WHtR, waist to height ratio | DBP, diastolic blood pressure | DZ, dizygotic | Amino acids | Cardiology and Cardiovascular Medicine | hs-CRP, high sensitivity C-reactive protein | HDL-C, high density lipoprotein cholesterol | Cardiometabolic | FFQ, food frequency questionnaire | Article | MZ, monozygotic | T2DM, type 2 diabetes | BCAA, branched chain amino acids | SBP, systolic blood pressure | Diet

Background: Conflicting data exist on the impact of dietary and circulating levels of branched chain amino acids (BCAA) on cardiometabolic health and it is unclear to what extent these relations are mediated by genetics. Methods: In a cross-sectional study of 1997 femal... View more
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