publication . Article . 2018

Administration of intravenous morphine for acute pain in the emergency department inflicts an economic burden in Europe

Casamayor, Montserrat; DiDonato, Karen; Hennebert, Marc; Brazzi, Luca; Prosen, Gregor;
Open Access English
  • Published: 01 Apr 2018 Journal: Drugs in Context, volume 7 (issn: 1740-4398, eissn: 1740-4398, Copyright policy)
  • Publisher: BioExcel Publishing Ltd
Abstract
Background: Acute pain is among the leading causes of referral to the emergency department (ED) in industrialized countries. Its management mainly depends on intensity. Moderateto- severe pain is treated with intravenous (IV) administered opioids, of which morphine is the most commonly used in the ED. We have estimated the burden of IV administration of morphine in the five key European countries (EU5) using a micro-costing approach. Scope: A structured literature review was conducted to identify clinical guidelines for acute pain management in EU5 and clinical studies conducted in the ED setting. The data identified in this literature review constituted the...
Subjects
free text keywords: acute pain, analgesia, pain management, emergency departments, morphine, RM1-950, Therapeutics. Pharmacology, nurse, Original Research, Europe; acute pain; analgesia; cost analysis; emergency departments; morphine; nurse; opioids; pain management, cost analysis, Europe, opioids
67 references, page 1 of 5

Cordell, WH, Keene, KK, Giles, BK, Jones, JB, Jones, EH, Brizendine, EJ. The high prevalence of pain in emergency medical care. Am J Emerg Med. 2002; 20: 165-9 [PubMed]

Todd, KH, Ducharme, J, Choiniere, M, Crandall, CS, Fosnocht, DE, Homel, P, Tanabe, P. Pain in the emergency department: results of the pain and emergency medicine initiative (PEMI) multicenter study. J Pain. 2007; 8: 460-6 [PubMed]

Todd, KH, Sloan, EP, Chen, C, Eder, S, Wamstad, K. Survey of pain etiology, management practices and patient satisfaction in two urban emergency departments. CJEM. 2002; 4: 252-6 [PubMed]

Boccard, E, Adnet, F, Gueugniaud, PY, Filipovics, A, Ricard-Hibon, A. Prise en charge de la douleur chez l’adulte dans des services d’urgences en France en 2010. Ann Fr Med Urgence. 2011; 1: 312-9

Macintyre, PE, Schug, SA, Scott, DA, Visser, EJ, Walker, SM. Acute Pain Management: Scientific Evidence. 2010

Pain service guidelines (adult). 2015

Protocolo de morfina parenteral urgencias de atención primaria. 2003

Clinical guideline for intravenous morphine administration in clinical areas for adults. 2015

Administration of bolus dose intravenous morphine. 2016

Clinical guidelines – Acute Pain Control WAHT-ANA-007.2015.

Clinical Practice Guideline: Difficult intravenous access. 2015

Witting, MD. IV access difficulty: incidence and delays in an urban emergency department. J Emerg Med. 2012; 42: 483-7 [PubMed]

Methoxyflurane (Penthrox) for emergency relief of moderate to severe pain. Horizon Scanning Review. 2016

Palmer, PP, Walker, JA, Patanwala, AE, Hagberg, CA, House, JA. Cost of intravenous analgesia for the management of acute pain in the emergency department is substantial in the United States. JHEOR. 2017; 5: 1-15

Rainer, TH, Jacobs, P, Ng, YC, Cheung, NK, Tam, M, Lam, PK, Wong, R, Cocks, RA. Cost effectiveness analysis of intravenous ketorolac and morphine for treating pain after limb injury: double blind randomised controlled trial. BMJ. 2000; 321: 1247-51 [OpenAIRE] [PubMed]

67 references, page 1 of 5
Abstract
Background: Acute pain is among the leading causes of referral to the emergency department (ED) in industrialized countries. Its management mainly depends on intensity. Moderateto- severe pain is treated with intravenous (IV) administered opioids, of which morphine is the most commonly used in the ED. We have estimated the burden of IV administration of morphine in the five key European countries (EU5) using a micro-costing approach. Scope: A structured literature review was conducted to identify clinical guidelines for acute pain management in EU5 and clinical studies conducted in the ED setting. The data identified in this literature review constituted the...
Subjects
free text keywords: acute pain, analgesia, pain management, emergency departments, morphine, RM1-950, Therapeutics. Pharmacology, nurse, Original Research, Europe; acute pain; analgesia; cost analysis; emergency departments; morphine; nurse; opioids; pain management, cost analysis, Europe, opioids
67 references, page 1 of 5

Cordell, WH, Keene, KK, Giles, BK, Jones, JB, Jones, EH, Brizendine, EJ. The high prevalence of pain in emergency medical care. Am J Emerg Med. 2002; 20: 165-9 [PubMed]

Todd, KH, Ducharme, J, Choiniere, M, Crandall, CS, Fosnocht, DE, Homel, P, Tanabe, P. Pain in the emergency department: results of the pain and emergency medicine initiative (PEMI) multicenter study. J Pain. 2007; 8: 460-6 [PubMed]

Todd, KH, Sloan, EP, Chen, C, Eder, S, Wamstad, K. Survey of pain etiology, management practices and patient satisfaction in two urban emergency departments. CJEM. 2002; 4: 252-6 [PubMed]

Boccard, E, Adnet, F, Gueugniaud, PY, Filipovics, A, Ricard-Hibon, A. Prise en charge de la douleur chez l’adulte dans des services d’urgences en France en 2010. Ann Fr Med Urgence. 2011; 1: 312-9

Macintyre, PE, Schug, SA, Scott, DA, Visser, EJ, Walker, SM. Acute Pain Management: Scientific Evidence. 2010

Pain service guidelines (adult). 2015

Protocolo de morfina parenteral urgencias de atención primaria. 2003

Clinical guideline for intravenous morphine administration in clinical areas for adults. 2015

Administration of bolus dose intravenous morphine. 2016

Clinical guidelines – Acute Pain Control WAHT-ANA-007.2015.

Clinical Practice Guideline: Difficult intravenous access. 2015

Witting, MD. IV access difficulty: incidence and delays in an urban emergency department. J Emerg Med. 2012; 42: 483-7 [PubMed]

Methoxyflurane (Penthrox) for emergency relief of moderate to severe pain. Horizon Scanning Review. 2016

Palmer, PP, Walker, JA, Patanwala, AE, Hagberg, CA, House, JA. Cost of intravenous analgesia for the management of acute pain in the emergency department is substantial in the United States. JHEOR. 2017; 5: 1-15

Rainer, TH, Jacobs, P, Ng, YC, Cheung, NK, Tam, M, Lam, PK, Wong, R, Cocks, RA. Cost effectiveness analysis of intravenous ketorolac and morphine for treating pain after limb injury: double blind randomised controlled trial. BMJ. 2000; 321: 1247-51 [OpenAIRE] [PubMed]

67 references, page 1 of 5
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publication . Article . 2018

Administration of intravenous morphine for acute pain in the emergency department inflicts an economic burden in Europe

Casamayor, Montserrat; DiDonato, Karen; Hennebert, Marc; Brazzi, Luca; Prosen, Gregor;