The First Total Synthesis of Dragmacidin D

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Garg, Neil K.; Sarpong, Richmond; Stoltz, Brian M.;
  • Publisher: American Chemical Society

The first total synthesis of the biologically significant bis-indole alkaloid dragmacidin D (5) has been achieved. Thermal and electronic modulation provides the key for a series of palladium-catalyzed Suzuki cross-coupling reactions that furnished the core structure of... View more
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