Immunostaining for Homer reveals the majority of excitatory synapses in laminae I–III of the mouse spinal dorsal horn

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Gutierrez-Mecinas, Maria; Kuehn, Emily D.; Abraira, Victoria E.; Polgár, Erika; Watanabe, Masahiko; Todd, Andrew J.;
  • Publisher: Elsevier Science
  • Journal: Neuroscience, volume 329, pages 171-181 (issn: 0306-4522, eissn: 1873-7544)
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  • Identifiers: doi: 10.1016/j.neuroscience.2016.05.009, pmc: PMC4915440
  • Subject: Neuroscience(all) | IB4, isolectin B4 | pain | DAB, diaminobenzidine | excitatory interneuron | CGRP, calcitonin gene-related peptide | Article | glutamatergic synapse | primary afferent | confocal microscopy | VGAT, vesicular GABA transporter | VGLUT2, vesicular glutamate transporter 2 | LTMR, low-threshold mechanoreceptor | VGLUT1, vesicular glutamate transporter 1 | spinal cord
    mesheuropmc: nervous system

The spinal dorsal horn processes somatosensory information before conveying it to the brain. The neuronal organization of the dorsal horn is still poorly understood, although recent studies have defined several distinct populations among the interneurons, which account ... View more
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