switchde: inference of switch-like differential expression along single-cell trajectories

Article English OPEN
Campbell, KR ; Yau, C (2016)
  • Publisher: Oxford University Press
  • Journal: Bioinformatics, volume 33, issue 8, pages 1,241-1,242 (issn: 1460-2059, eissn: 1367-4811)
  • Related identifiers: doi: 10.1093/bioinformatics/btw798, pmc: PMC5408844
  • Subject: Applications Notes | Gene Expression

MOTIVATION: Pseudotime analyses of single-cell RNA-seq data have become increasingly common. Typically, a latent trajectory corresponding to a biological process of interest - such as differentiation or cell cycle - is discovered. However, relatively little attention ha... View more