Antibody responses to Borrelia burgdorferi detected by western blot vary geographically in Canada.

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Nicholas H Ogden; Julie Arsenault; Todd F Hatchette; Samir Mechai; L Robbin Lindsay;
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 12,issue 2 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: pmc: PMC5300191, doi: 10.1371/journal.pone.0171731
  • Subject: Microbial Pathogens | Applied Mathematics | Algorithms | Research Article | Earth Sciences | Bacteria | Mathematics | Manitoba | Infectious Diseases | Rheumatology | Pathology and Laboratory Medicine | Geographical locations | Borrelia | Borrelia Infection | Simulation and Modeling | Physical Sciences | Pathogens | Lyme Disease | People and places | North America | Ontario | Geography | Biology and Life Sciences | Research and Analysis Methods | Microbiology | Research Laboratories | Medicine | Bacterial Pathogens | Government Laboratories | Bacterial Diseases | Medical Microbiology | Q | R | Canada | Social Sciences | Science | Organisms | Medicine and Health Sciences | Research Facilities | Human Geography | Borrelia Burgdorferi

Lyme disease is emerging in eastern and central Canada, and most cases are diagnosed using the two-tier serological test (Enzyme Immuno Assay [EIA] followed by Western blot [WB]). Simplification of this algorithm would be advantageous unless it impacts test performance.... View more
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