Depletion of Plasmodium berghei Plasmoredoxin Reveals a Non-Essential Role for Life Cycle Progression of the Malaria Parasite

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Kathrin Buchholz; Stefan Rahlfs; R Heiner Schirmer; Katja Becker; Kai Matuschewski;
  • Publisher: Public Library of Science
  • Journal: PLoS ONE,volume 3,issue 6 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC2429964, doi: 10.1371/journal.pone.0002474
  • Subject: Q | R | Cell Biology/Microbial Growth and Development | Research Article | Infectious Diseases/Protozoal Infections | Science | Microbiology/Parasitology | Medicine | Microbiology/Cellular Microbiology and Pathogenesis
    mesheuropmc: parasitic diseases

Proliferation of the pathogenic Plasmodium asexual blood stages in host erythrocytes requires an exquisite capacity to protect the malaria parasite against oxidative stress. This function is achieved by a complex antioxidant defence system composed of redox-active prote... View more
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