Depletion of Plasmodium berghei plasmoredoxin reveals a non-essential role for life cycle progression of the malaria parasite.

Article English OPEN
Kathrin Buchholz ; Stefan Rahlfs ; R Heiner Schirmer ; Katja Becker ; Kai Matuschewski
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE, volume 3, issue 6 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: pmc: PMC2429964, doi: 10.1371/journal.pone.0002474
  • Subject: Q | Cell Biology/Microbial Growth and Development | R | Research Article | Infectious Diseases/Protozoal Infections | Science | Microbiology/Parasitology | Medicine | Microbiology/Cellular Microbiology and Pathogenesis
    mesheuropmc: parasitic diseases

Proliferation of the pathogenic Plasmodium asexual blood stages in host erythrocytes requires an exquisite capacity to protect the malaria parasite against oxidative stress. This function is achieved by a complex antioxidant defence system composed of redox-active prote... View more
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