Detection of microsatellite instability but not truncating APC mutations in gastric adenocarcinomas in Brazilian patients

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Roberta A.U. Bevilacqua; Cassandra M. Corvello; Ana Paula Duarte; Andrew J.G. Simpson;

A crucial role for the adenomatous polyposis colonic (APC) gene in colorectal carcinogenesis has been conclusively established, but, the role of APC in gastric tumors remains controversial. APC mutations have been detected at a relatively high frequency in gastric tumor... View more