IL-21/IL-21R signaling suppresses intestinal inflammation induced by DSS through regulation of Th responses in lamina propria in mice

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Yuanyuan Wang; Xuefeng Jiang; Junfeng Zhu; Dan Yue; Xiaoqing Zhang; Xiao Wang; Yong You; Biao Wang; Ying Xu; Changlong Lu; Xun Sun; Yasunobu Yoshikai;

Serum level of IL-21 is increased in patients with inflammatory bowel diseases (IBD), suggesting that IL-21/IL-21 receptor (IL-21R) signaling may be involved in the pathogenesis of IBD. However, the role of IL-21/IL-21 receptor signaling plays in the pathogenesis of IBD... View more
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