A metastasis biomarker (MetaSite Breast™ Score) is associated with distant recurrence in hormone receptor-positive, HER2-negative early-stage breast cancer

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Joseph A. Sparano; Robert Gray; Maja H. Oktay; David Entenberg; Thomas Rohan; Xiaonan Xue; Michael Donovan; Michael Peterson; Anthony Shuber; Douglas A. Hamilton; Timothy D’Alfonso; Lori J. Goldstein; Frank Gertler; Nancy E. Davidson; John Condeelis; Joan Jones;

Metastasis is the primary cause of death in early-stage breast cancer. We evaluated the association between a metastasis biomarker, which we call "Tumor Microenviroment of Metastasis" (TMEM), and risk of recurrence. TMEM are microanatomic structures where invasive tumor... View more
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