A metastasis biomarker (MetaSite Breast™ Score) is associated with distant recurrence in hormone receptor-positive, HER2-negative early-stage breast cancer

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Sparano, Joseph A.; Gray, Robert; Oktay, Maja H.; Entenberg, David; Rohan, Thomas; Xue, Xiaonan; Donovan, Michael; Peterson, Michael; Shuber, Anthony; Hamilton, Douglas A.; D’Alfonso, Timothy; Goldstein, Lori J.; Gertler, Frank; Davidson, Nancy E.; Condeelis, John; Jones, Joan;
  • Publisher: Springer Nature
  • Journal: volume 3issn: 2374-4677, eissn: 2374-4677
  • Related identifiers: doi: 10.1038/S41523-017-0043-5, pmc: PMC5678158
  • Subject: RC254-282 | Article | Neoplasms. Tumors. Oncology. Including cancer and carcinogens

Metastasis is the primary cause of death in early-stage breast cancer. We evaluated the association between a metastasis biomarker, which we call “Tumor Microenviroment of Metastasis” (TMEM), and risk of recurrence. TMEM are microanatomic structures where invasive tumor... View more
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