Influence of XRCC1 Genetic Polymorphisms on Ionizing Radiation-Induced DNA Damage and Repair

Article, Review English OPEN
Sterpone, Silvia ; Cozzi, Renata (2010)
  • Publisher: SAGE-Hindawi Access to Research
  • Journal: Journal of Nucleic Acids, volume 2,010 (issn: 2090-021X, eissn: 2090-021X)
  • Related identifiers: pmc: PMC2925273, doi: 10.4061/2010/780369
  • Subject: Review Article | QH426-470 | Genetics | QD415-436 | Biochemistry | Article Subject

It is well known that ionizing radiation (IR) can damage DNA through a direct action, producing single- and double-strand breaks on DNA double helix, as well as an indirect effect by generating oxygen reactive species in the cells. Mammals have evolved several and disti... View more
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