Contribution of Mouse Embryonic Stem Cells and Induced Pluripotent Stem Cells to Chimeras through Injection and Coculture of Embryos

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Guo, Jitong; Wu, Baojiang; Li, Shuyu; Bao, Siqin; Zhao, Lixia; Hu, Shuxiang; Sun, Wei; Su, Jie; Dai, Yanfeng; Li, Xihe;

Blastocyst injection and morula aggregation are commonly used to evaluate stem cell pluripotency based on chimeric contribution of the stem cells. To assess the protocols for generating chimeras from stem cells, 8-cell mouse embryos were either injected or cocultured wi... View more
  • References (54)
    54 references, page 1 of 6

    Tarkowski, A. K.. Mouse chimæras developed from fused eggs. Nature. 1961; 190 (4779): 857-860

    Gardner, R. L.. Mouse chimaeras obtained by the injection of cells into the blastocyst. Nature. 1968; 220 (5167): 596-597

    Wood, S. A., Allen, N. D., Rossant, J., Auerbach, A., Nagy, A.. Non-injection methods for the production of embryonic stem cell-embryo chimaeras.. Nature. 1993; 365 (6441): 87-89

    Wood, S. A., Pascoe, W. S., Schmidt, C., Kemler, R., Evans, M. J., Allen, N. D.. Simple and efficient production of embryonic stem cell-embryo chimeras by coculture. Proceedings of the National Academy of Sciences of the United States of America. 1993; 90 (10): 4582-4585

    Moustafa, L. A., Brinster, R. L.. Induced chimaerism by transplanting embryonic cells into mouse blastocysts. Journal of Experimental Zoology. 1972; 181 (2): 193-201

    Nagy, A., Gertsenstein, M., Vintersten, K., Behringer, R.. Manipulating the Mouse Embryo: A Laboratory Manual. 2003

    Mintz, B., Illmensee, K.. Normal genetically mosaic mice produced from malignant teratocarcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 1975; 72 (9): 3585-3589

    Bradley, A., Evans, M., Kaufman, M. H., Robertson, E.. Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines. Nature. 1984; 309 (5965): 255-256

    Matsui, Y., Zsebo, K., Hogan, B. L. M.. Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture. Cell. 1992; 70 (5): 841-847

    Wakayama, T., Tabar, V., Rodriguez, I., Perry, A. C. F., Studer, L., Mombaerts, P.. Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer. Science. 2001; 292 (5517): 740-743

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