Positive selection on schizophrenia-associated ST8SIA2 gene in post-glacial Asia

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Fujito, Naoko T.; Satta, Yoko; Hane, Masaya; Matsui, Atsushi; Yashima, Kenta; Kitajima, Ken; Sato, Chihiro; Takahata, Naoyuki; Hayakawa, Toshiyuki;
(2018)
  • Publisher: Public Library of Science
  • Journal: PLoS ONE,volume 13,issue 7 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: pmc: PMC6059407, doi: 10.1371/journal.pone.0200278
  • Subject: Molecular Biology | Research Article | Data Management | Geographical Locations | Schizophrenia | Taxonomy | Mental Health and Psychiatry | Artificial Gene Amplification and Extension | Phylogenetic Analysis | Genetics | Evolutionary Biology | People and Places | Molecular Biology Techniques | Phylogenetics | Genomics | Sequence Analysis | Evolutionary Systematics | Database and Informatics Methods | Polymerase Chain Reaction | Molecular Genetics | Sequence Databases | Biology and Life Sciences | Computer and Information Sciences | Biological Databases | Research and Analysis Methods | Asia | Medicine | Heredity | Q | R | Haplotypes | Mammalian Genomics | Genetic Mapping | Science | Bioinformatics | Animal Genomics | Medicine and Health Sciences

A number of loci are associated with highly heritable schizophrenia and the prevalence of this mental illness has had considerable negative fitness effects on human populations. Here we focused on one particular schizophrenia-associated gene that encodes a sialyltransfe... View more
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