Monitoring of an RNA Multistep Folding Pathway by Isothermal Titration Calorimetry

Article, Other literature type English OPEN
Reymond, Cédric; Bisaillon, Martin; Perreault, Jean-Pierre;
(2009)

Isothermal titration calorimetry was used to monitor the energetic landscape of a catalytic RNA, specifically that of the hepatitis delta virus ribozyme. Using mutants that isolated various tertiary interactions, the thermodynamic parameters of several ribozyme-substrat... View more
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