A single exercise bout enhances the manufacture of viral-specific T-cells from healthy donors: implications for allogeneic adoptive transfer immunotherapy

Article English OPEN
Guillaume Spielmann; Catherine M. Bollard; Hawley Kunz; Patrick J. Hanley; Richard J. Simpson;
  • Publisher: Nature Publishing Group
  • Journal: Scientific Reports,volume 6 (issn: 2045-2322, eissn: 2045-2322)
  • Related identifiers: pmc: PMC4867645, doi: 10.1038/srep25852
  • Subject: Article
    mesheuropmc: hemic and lymphatic diseases | virus diseases

Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) infections remain a major cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). The adoptive transfer of donor-derived viral-specific cytotoxic T-cells (VSTs) is an effective ... View more
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