Estrogen receptor beta as a novel target of androgen receptor action in breast cancer cell lines

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Rizza, Pietro; Barone, Ines; Zito, Domenico; Giordano, Francesca; Lanzino, Marilena; De Amicis, Francesca; Mauro, Loredana; Sisci, Diego; Catalano, Stefania; Wright, Karin Dahlman; Gustafsson, Jan-ake; Andò, Sebastiano;
  • Publisher: BioMed Central
  • Journal: Breast Cancer Research : BCR,volume 16,issue 1,pagesR21-R21 (issn: 1465-5411, eissn: 1465-542X)
  • Related identifiers: doi: 10.1186/bcr3619, pmc: PMC3978907
  • Subject: Research Article | Medicine(all)

Introduction The two isoforms of estrogen receptor (ER) alpha and beta play opposite roles in regulating proliferation and differentiation of breast cancers, with ER-alpha mediating mitogenic effects and ER-beta acting as a tumor suppressor. Emerging data have reported ... View more
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