Cardiovascular and Renal Outcomes of Renin–Angiotensin System Blockade in Adult Patients with Diabetes Mellitus: A Systematic Review with Network Meta-Analyses

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Ferrán Catalá-López; Diego Macías Saint-Gerons; Diana González-Bermejo; Giuseppe M Rosano; Barry R Davis; Manuel Ridao; Abel Zaragoza; Dolores Montero-Corominas; Aurelio Tobías; César de la Fuente-Honrubia; Rafael Tabarés-Seisdedos; Brian Hutton;
  • Publisher: Public Library of Science
  • Journal: PLoS Medicine, volume 13, issue 3 (issn: 1549-1277, eissn: 1549-1676)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1371/journal.pmed.1001971, pmc: PMC4783064
  • Subject: Research Article | Pharmaceutics | Mathematics | Myocardial Infarction | Renal Diseases | Diabetes Mellitus | Mathematical and Statistical Techniques | Endocrine Disorders | Nephrology | Physical Sciences | ACE inhibitor therapy | sistema cardiovascular | Pharmacology | Metabolic Disorders | Cardiovascular therapy | Heart Failure | Statistics (Mathematics) | Biology and life sciences | Drug therapy | Drugs | Research and Analysis Methods | Meta-Analysis | Medicine | ACE inhibitors | Enzymology | Cardiology | R | Diuretics | Biochemistry | Medicine and Health Sciences | Enzyme inhibitors | Statistical Methods | Endocrinology

Editors' Summary Background Chronic high blood pressure can damage blood vessels, heart, and kidneys, and cause cardiovascular and kidney (or renal) disease. Diabetes increases the risk for high blood pressure. An estimated two-thirds of adults with diabetes have high b... View more
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