An HRE-binding Py-Im polyamide impairs hypoxic signaling in tumors

Other literature type, Article OPEN
Szablowski, Jerzy O.; Raskatov, Jevgenij A.; Dervan, Peter B.;
(2015)

Hypoxic gene expression contributes to the pathogenesis of many diseases, including organ fibrosis, age-related macular degeneration, and cancer. Hypoxia-inducible factor-1 (HIF1), a transcription factor central to the hypoxic gene expression, mediates multiple processe... View more
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