Network effects of subthalamic deep brain stimulation drive a unique mixture of responses in basal ganglia output

Article, Review English OPEN
Humphries, Mark D; Gurney, Kevin;
  • Related identifiers: doi: 10.1111/j.1460-9568.2012.08085.x
  • Subject: Neuroscience(all) | Basal ganglia | /dk/atira/pure/subjectarea/asjc/2800 | High-frequency stimulation | Parkinson's disease
    mesheuropmc: nervous system diseases | therapeutics | nervous system | surgical procedures, operative

Deep brain stimulation (DBS) is a remarkably successful treatment for the motor symptoms of Parkinson's disease. High-frequency stimulation of the subthalamic nucleus (STN) within the basal ganglia is a main clinical target, but the physiological mechanisms of therapeut... View more
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