Functional Advantages of Conserved Intrinsic Disorder in RNA-Binding Proteins

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Varadi, Mihaly ; Zsolyomi, Fruzsina ; Guharoy, Mainak ; Tompa, Peter (2015)
  • Publisher: Public Library of Science
  • Journal: PLoS ONE, volume 10, issue 10 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: doi: 10.1371/journal.pone.0139731, pmc: PMC4595337
  • Subject: Q | R | Research Article | Science | Medicine

Proteins form large macromolecular assemblies with RNA that govern essential molecular processes. RNA-binding proteins have often been associated with conformational flexibility, yet the extent and functional implications of their intrinsic disorder have never been full... View more
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