Silica-Coated Liposomes for Insulin Delivery

Article English OPEN
Dwivedi, Neelam; Arunagirinathan, M. A.; Sharma, Somesh; Bellare, Jayesh;
  • Publisher: Hindawi Publishing Corporation
  • Journal: Journal of Nanomaterials (issn: 1687-4110, eissn: 1687-4129)
  • Related identifiers: doi: 10.1155/2010/652048
  • Subject: Technology (General) | T1-995 | Article Subject

Liposomes coated with silica were explored as protein delivery vehicles for their enhanced stability and improved encapsulation efficiency. Insulin was encapsulated within the fluidic phosphatidylcholine lipid vesicles by thin film hydration at pH 2.5, and layer of sili... View more
  • References (48)
    48 references, page 1 of 5

    Victor, S. P., Sampath Kumar, T. S.. BCP ceramic microspheres as drug delivery carriers: synthesis, characterisation and doxycycline release. Journal of Materials Science: Materials in Medicine. 2008; 19 (1): 283-290

    Porter, C. J. H., Pouton, C. W., Cuine, J. F., Charman, W. N.. Enhancing intestinal drug solubilisation using lipid-based delivery systems. Advanced Drug Delivery Reviews. 2008; 60 (6): 673-691

    Shapira, I., Budman, D. R., Bradley, T., Gralla, R.. Evolving lipid-based delivery systems in the management of neoplastic disease. Oncology Reviews. 2009; 3 (2): 113-124

    Tan, A., Simovic, S., Davey, A. K., Rades, T., Prestidge, C. A.. Silica-lipid hybrid (SLH) microcapsules: a novel oral delivery system for poorly soluble drugs. Journal of Controlled Release. 2009; 134 (1): 62-70

    Simovic, S., Heard, P., Hui, H.. Dry hybrid lipid-silica microcapsules engineered from submicron lipid droplets and nanoparticles as a novel delivery system for poorly soluble drugs. Molecular Pharmaceutics. 2009; 6 (3): 861-872

    Gupta, G., Lopez, G. P., Atanassov, P.. Hybrid materials based on silica/lipid assemblies with incorporation of transmembrane proteins. : 14231

    Lincopan, N., Santana, M. R. A., Faquim-Mauro, E., da Costa, M. H. B., Carmona-Ribeiro, A. M.. Silica-based cationic bilayers as immunoadjuvants. BMC Biotechnology. 2009; 9, article 5

    Liu, J., Stace-Naughton, A., Jiang, X., Brinker, C. J.. Porous nanoparticle supported lipid bilayers (protocells) as delivery vehicles. Journal of the American Chemical Society. 2009; 131 (4): 1354-1355

    Bégu, S., Girod, S., Lerner, D. A., Jardiller, N., Tourné-Péteilh, C., Devoisselle, J.-M.. Characterization of a phospholipid bilayer entrapped into non-porous silica nanospheres. Journal of Materials Chemistry. 2004; 14 (8): 1316-1320

    Li, Y., Mitra, A. K.. Effects of phospholipid chain length, concentration, charge, and vesicle size on pulmonary insulin absorption. Pharmaceutical Research. 1996; 13 (1): 76-79

  • Metrics
    No metrics available
Share - Bookmark