Thirty Years of Orphan Drug Legislation and the Development of Drugs to Treat Rare Seizure Conditions: A Cross Sectional Analysis

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Döring, Jan Henje; Lampert, Anette; Hoffmann, Georg F.; Ries, Markus;
  • Publisher: Public Library of Science
  • Journal: PLoS ONE,volume 11,issue 8 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1371/journal.pone.0161660, pmc: PMC4996488
  • Subject: Epilepsy | Research Article | Pharmaceutics | Drug Therapy | Drug Administration | Drugs | Diazepam | Myoclonic Seizures | Tonic-Clonic Seizures | Medicine | Drug Research and Development | Drug Marketing | Q | R | Epileptic Seizures | Science | Pharmacology | Medicine and Health Sciences | Neurology

Background Epilepsy is a serious chronic health condition with a high morbidity impairing the life of patients and afflicted families. Many epileptic conditions, especially those affecting children, are rare disorders generating an urgent medical need for more efficacio... View more
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