Properties of an Oral Preparation Containing a Chitosan Salt

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Murata, Yoshifumi; Kodama, Youko; Hirai, Daijirou; Kofuji, Kyouko; Kawashima, Susumu;
  • Publisher: MDPI AG
  • Journal: Molecules,volume 14,issue 2,pages755-762 (issn: 1420-3049, eissn: 1420-3049)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC6253835, doi: 10.3390/molecules14020755
  • Subject: Chitosan, 2-(4-Chlorophenoxy)-2-methylpropionic acid | Bile acid adsorption | Chitosan | Hyperlipidemia. | Hyperlipidemia | 2-(4-Chlorophenoxy)-2-methylpropionic acid | Organic chemistry | QD241-441 | Drug release | Communication
    mesheuropmc: carbohydrates (lipids)

The 2-(4-chlorophenoxy)-2-methylpropionic acid (CMP) salt of chitosan (CS), CS-CMP, and that of a CS derivative (CP), were prepared and their ability to adsorb bile acids investigated. CS-CMP and CP-CMP rapidly adsorbed taurocholate (TCA) and glycocholate (GCA) when the... View more
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