Cross-Linking in Collagen by Nonenzymatic Glycation Increases the Matrix Stiffness in Rabbit Achilles Tendon

Article English OPEN
Reddy, G. Kesava (2004)
  • Publisher: Hindawi Publishing Corporation
  • Journal: Experimental Diabesity Research, volume 5, issue 2, pages 143-153 (issn: 1543-8600, eissn: 1543-8619)
  • Related identifiers: doi: 10.1080/15438600490277860, pmc: PMC2496877
  • Subject: Research Article
    mesheuropmc: musculoskeletal system | musculoskeletal diseases

Nonenzymatic glycation of connective tissue matrix proteins is a major contributor to the pathology of diabetes and aging. Previously the author and colleagues have shown that nonenzymatic glycation significantly enhances the matrix stability in the Achilles tendon (Red... View more
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