Serum Progranulin as an Independent Marker of Liver Fibrosis in Patients with Biopsy-Proven Nonalcoholic Fatty Liver Disease

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Yilmaz, Yusuf; Eren, Fatih; Yonal, Oya; Polat, Zulfikar; Bacha, Mohammad; Kurt, Ramazan; Ozturk, Oguzhan; Avsar, Erol;
  • Publisher: IOS Press
  • Journal: Disease Markers,volume 31,issue 4,pages205-210 (issn: 0278-0240, eissn: 1875-8630)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC3826876, doi: 10.3233/DMA-2011-0815
  • Subject: Other | nonalcoholic fatty liver disease | R5-920 | enzyme-linked immunosorbent assay | Medicine (General) | Progranulin | hepatic fibrosis
    mesheuropmc: digestive system diseases | nutritional and metabolic diseases | mental disorders

Background: Elevated progranulin levels are associated with visceral obesity, elevated plasma glucose, and dyslipidemia. Progranulin has not been previously investigated as a biomarker of nonalcoholic fatty liver disease (NAFLD). We sought to determine whether serum pro... View more
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