Colorectal cancer and long-term exposure to trihalomethanes in drinking water: a multicenter case-control study in Spain and Italy

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Villanueva, C.M. ; Gracia-Lavedan, E. ; Bosetti, C. ; Righi, E. ; Molina, A.J. ; Martín, V. ; Boldo, E. ; Aragonés, N. ; Perez-Gomez, B. ; Pollan, M. ; Gomez Acebo, I. ; Altzibar, J.M. ; Jiménez Zabala, A. ; Ardanaz, E. ; Peiró, R. ; Tardón, A. ; Chirlaque, M.D. ; Tavani, A. ; Polesel, J. ; Serraino, D. ; Pisa, F. ; Castaño-Vinyals, G. ; Espinosa, A. ; Espejo-Herrera, N. ; Palau, M. ; Moreno, V. ; La Vecchia, C. ; Aggazzotti, G. ; Nieuwenhuijsen, M.J. ; Kogevinas, M. (2017)
  • Publisher: Public Health Services, US Dept of Health and Human Services
  • Journal: volume 125, issue 1, pages 56-65 (issn: 0091-6765, eissn: 1552-9924)
  • Related identifiers: doi: 10.1289/EHP155, pmc: PMC5226692
  • Subject: Spain | Colorectal cancer | Aigua potable | Còlon -- Càncer | Research | Càncer colorectal | colorectal cancer, trihalomethanes, drinking water, Italy, Spain, case-control study | Settore MED/01 - Statistica Medica | Itàlia | Drinking water | Aigua -- Contaminació | Espanya | Italy

Background: Evidence on the association between colorectal cancer and exposure to disinfection by-products in drinking water is inconsistent. Objectives: We assessed long-term exposure to trihalomethanes (THMs), the most prevalent group of chlorination by-products, to e... View more