Establishment of a yeast platform strain for production of p-coumaric acid through metabolic engineering of aromatic amino acid biosynthesis

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Rodriguez Prado, Edith Angelica ; Kildegaard, Kanchana Rueksomtawin ; Li, Mingji ; Borodina, Irina ; Nielsen, Jens (2015)
  • Publisher: Elsevier BV
  • Journal: volume 31, pages 181-188 (issn: 1096-7176)
  • Related identifiers: doi: 10.1016/j.ymben.2015.08.003
  • Subject: Biotechnology | Shikimate kinase | Applied Microbiology and Biotechnology | p-Coumaric acid | Bioengineering | Saccharomyces cerevisiae

Aromatic amino acids are precursors of numerous plant secondary metabolites with diverse biological functions. Many of these secondary metabolites are already being used as active pharmaceutical or nutraceutical ingredients, and there are numerous exploratory studies of... View more
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