publication . Article . 1995

Sexual dimorphism of stress response and immune/ inflammatory reaction: the corticotropin releasing hormone perspective

Nicholas V. Vamvakopoulos;
Open Access English
  • Published: 01 Jan 1995 Journal: Mediators of Inflammation, volume 4, issue 3, pages 163-174 (issn: 0962-9351, eissn: 1466-1861, Copyright policy)
  • Publisher: Hindawi Publishing Corporation
Abstract
This review higlghts key aspects of corticotropin releasing hormone (CRH) biology of potential relevance to the sexual dimorphism of the stress response and immune/inflammatory reaction, and introduces two important new concepts based on the regulatory potential of the human (h) CRH gene: (1) a proposed mechanism to account for the tissue-specific antithetical responses of hCRH gene expression to glucocorticolds, that may also explain the frequently observed antithetical effects of chronic glucocorticoid administration in clinical practice and (2) a heuristic diagram to illustrate the proposed modulation of the stress response and immune/ inflammatory reaction b...
Subjects
mesheuropmc: endocrine systemhormones, hormone substitutes, and hormone antagonists
free text keywords: RB1-214, Pathology, Research Article
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publication . Article . 1995

Sexual dimorphism of stress response and immune/ inflammatory reaction: the corticotropin releasing hormone perspective

Nicholas V. Vamvakopoulos;