Uncarinic Acid C Isolated from Uncaria rhynchophylla Induces Differentiation of Th1-Promoting Dendritic Cells Through TLR4 Signaling

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Kyu Sik Kim; Thanh Nhan Nguyen Pham; Chun-Ji Jin; Akemi Umeyama; Noboru Shoji; Toshihiro Hashimoto; Je-Jung Lee; Masao Takei;

Uncarinic acid C (URC) is triterpene isolated from Uncaria rhynchophylla and is a pharmacologically active substance. The induction of dendritic cells (DC) is critical for the induction of Ag-specific T lymphocyte responses and may be essential for the development of hu... View more
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