Acidosis activates complement system in vitro

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Emeis, M; Sonntag, J; Willam, C; Strauss, E; Walka, M M; Obladen, M;
(1998)

We investigated the in vitro effect of different forms of acidosis (pH 7.0) on the formation of anaphylatoxins C3a and C5a. Metabolic acidosis due to addition of hydrochloric acid (10 micromol/ml blood) or lactic acid (5.5 micromol/ml) to heparin blood (N=12) caused sig... View more
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