Ensemble coding of context-dependent fear memory in the amygdala

Article English OPEN
Orsini, Caitlin A. ; Yan, Chen ; Maren, Stephen (2013)
  • Publisher: Frontiers Media S.A.
  • Journal: Frontiers in Behavioral Neuroscience, volume 7 (issn: 1662-5153, eissn: 1662-5153)
  • Related identifiers: pmc: PMC3861741, doi: 10.3389/fnbeh.2013.00199, doi: 10.3389/fnbeh.2013.00199/full
  • Subject: amygdala | hippocampus | Neurosciences. Biological psychiatry. Neuropsychiatry | renewal | prefrontal cortex | RC321-571 | Neuroscience | extinction | Arc | context | Original Research Article | fear
    mesheuropmc: nervous system

After fear conditioning, presenting the conditioned stimulus (CS) alone yields a context-specific extinction memory; fear is suppressed in the extinction context, but renews in any other context. The context-dependence of extinction is mediated by a brain circuit consi... View more