Binary and ternary cocrystals of sulfa drug acetazolamide with pyridine carboxamides and cyclic amides

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Bolla, Geetha; Nangia, Ashwini; (2016)
  • Publisher: International Union of Crystallography
  • Journal: IUCrJ,volume 3,issue Pt 2,pages152-160 (issn: 2052-2525, eissn: 2052-2525)
  • Related identifiers: pmc: PMC4775163, doi: 10.1107/S2052252516000543
  • Subject: hydrogen bonding | Q | Science | Research Papers | pharmaceutical solids | crystal engineering | co-crystals | crystal design

A novel design strategy for cocrystals of a sulfonamide drug with pyridine carboxamides and cyclic amides is developed based on synthon identification as well as size and shape match of coformers. Binary adducts of acetazolamide (ACZ) with lactams (valerolactam and capr... View more
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